type 2 diabetes mellitus
Conditions
Interventions
group 1:insulin aspart 30
group 2:insulin aspart 50
Sponsors
The 1st Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Eligible patients will be men and women with type 2 diabetes mellitus, aged 18-80 years old, body mass index of 18-35kg/m2, an HbA1c of 7-11.0%, fasting c-peptipe >0.8ng/ml, blood glucose level is poorly controlled with merformin and sulfonylureas, and with or without alpha-glucosidase inhibitor.
Exclusion criteria
Exclusion criteria: patients who had used aspart 30/50 during the preceding 1 month are not eligible for this studyindividuals who had severe diabetes mellitus complication or infection during the preceding 1 monthimpaired hepatic function (alanine aminotransferase >=3 times upper limit),or impaired kidney function (GFR<30ml/(min*1.73m^2)), had surgery, pregnant or have a intention to be pregnant within 6 months or within lactation periodhad severe mental disorders such as schizophrenia or had tumor are also not eligible for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c; | — |
Secondary
| Measure | Time frame |
|---|---|
| percentage of qualified patients;fasting plasma glucose;blood glucose;dosage of insulin;c peptide;body mass index;HOMA-beta;HOMA-IR;rate of hypoglycemic;oral hypoglycemic agent; | — |
Countries
China
Contacts
Public ContactRan Bai
The 1st Affiliated Hospital of Dalian Medical University
Outcome results
None listed