migraine
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female non-premonitory migraine patients between 18-65 years old; 2. Diagnosed as migraine according to the diagnostic criteria specified by the International Classification of Headache Disorder, 3rd edition (beta version) and initial of age is less than 50 years old; 3. Migraine present for at least three years and patients having 2-6 attacks per month; 4. Moderate to severe pain (VAS=3.6) which affected the work and learning; 5. No prophylactic drugs of migraine such as beta-blockerscalcium channel blockersantiepileptic drugs and son on were taken in the past 3 months.
Exclusion criteria
Exclusion criteria: 1. Having analgesics more than 10 times due to the migraine attacks every month; 2. Special types of migraine such as ophthalmoplegia hemiplegic migraine type; 3. Cluster headache,tension-type headache and other secondary headache disorders; 4. Pregnancy and lactation women; 5. Combined with hepaticrenal hematopoietic system and other serous primary diseases, hypertension and diabetes mellitus; 6. Having severe mental disease; 7. Allergic constitution; 8. Refused to sign the consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| attack frequency; | — |
Secondary
| Measure | Time frame |
|---|---|
| duration of each attack;fasting blood glucose;glycosylated hemoglobin.;the severity of migraine measured by VAS score during the attack.; | — |
Countries
China
Contacts
Harbin Medical University