Hypotension
Conditions
Interventions
Two groups:Norepinephrine versus phenylephrine, Intravenous infusion. Norepinephrine 7.5 mcg/ml, Approx 30 min
phenylephrine 100 mcg/ml Approx 30 min
Sponsors
The Chinese University of Hong Kong
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologists physical status 1-2 patients scheduled for elective caesarean section at = 36 weeks of gestation under spinal anaesthesia during normal working hours at Prince of Wales Hospital, Shatin, Hong Kong.
Exclusion criteria
Exclusion criteria: Known fetal abnormality, inability or refusal to give informed consent, age 100 kg, preexisting or pregnancy-induced hypertension, patients taking monoamine oxidase inhibitors or tricyclic antidepressants, patients with mesenteric or peripheral vascular thrombosis, patients with renal impairment, known allergy to phenylephrine or norepinephrine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of HR recordings less than 60 beats/min during the interval from induction of anaesthesia to fetal delivery; | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Precision of BP control assessing using performance error calcuations;2. Neonatal Apgar scores;3. Umbilical arterial and venous blood gases; | — |
Countries
China
Contacts
Public ContactNGAN KEE Warwick Dean
The Chinese University of Hong Kong
Outcome results
None listed