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Efficacy and safety of a new dentifrice containing Chinese herb extracts for dentin hypersensitivity: a double-blind randomized placebo parallel controlled trial

Efficacy and safety of a new dentifrice containing Chinese herb extracts for dentin hypersensitivity: a double-blind randomized placebo parallel controlled trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IIR-16008491
Enrollment
Unknown
Registered
2016-05-18
Start date
2016-05-25
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dentin hypersensitivity

Interventions

Sponsors

Sichuan University, West China Hospital of Stomatology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1, ages 18 to 65 years, gender not limited; 2, the whole body is in good condition, for commercial dental products or cosmetics allergy; 3, conform to dentine hypersensitivity diagnosis and research for anterior teeth or premolar, dentine hypersensitivity site for buccal tooth neck, the cause of dentine hypersensitivity to wear or gum back; 4, depending on the diagnosis or explore diagnosis can clear judgment dentin exposure without caries filling body, no odontoclasis and cracked, pulpitis symptoms; 5, pain to distinguish ability, and at least one of dentine hypersensitivity of teeth, sensitive to 10 g ~ 50 g of tactile stimuli, and (or) cold air stimulation VAS score of 2 or more points; 6, voluntarily signed informed consent.

Exclusion criteria

Exclusion criteria: 1, sensitive teeth are fixed or removable partial denture abutment teeth, with a full crown, or tooth enamel have obvious crack;Sensitive teeth loose degree > 1 degree; 2, poor oral hygiene status, severe gum inflammation or need comprehensive dental treatment; 3, the last six months had periodontal surgery treatment in recent 3 months to accept blow cure or dental root surface smooth; 4, 2 weeks before the test screening underwent for the treatment of gum on clean governance; 5, have caused chronic diseases of intermittent or continuous, such as arthritis, etc.; 6, within a month before the test taken convulsion, antihistamines, composed, tranquilizers, antidepressants, 1 weeks taking anti-inflammatory drugs, daily painkillers, or need to start taking the drug during the test; 7, women during pregnancy or lactation; 8, not suitable for the group, researchers make decision.

Design outcomes

Primary

MeasureTime frame
Explore clinical diagnostic sensitivity pressure and its decline in value;Cold air blow after spraying stimulus score and the decline in value;Blow cold water spray;

Countries

China

Contacts

Public ContactHu Tao

West China Hospital of Stomatology, Sichuan University

hutao@scu.edu.cn+86 13980891100

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026