polycystic ovarian syndrome
Conditions
Interventions
Sponsors
The third affiliated hospital of Guangzhou Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: All PCOS patients met all three criteria of the revised 2003 Rotterdam European Society of Human Reproduction and Embryology (ESHRE)/American Society of Reproductive Medicine (ASRM) PCOS Consensus Workshop Group diagnostic criteria. The three criteria are 1. oligo- and/or anovulation; 2. clinical and/or biochemical signs of hyperandrogenism, and 3. ultrasound appearance of polycystic ovaries with the exclusion of other known causes of hyperandrogenemia and ovulatory dysfunction including 21-hydroxylase deficiency, congenital adrenal hyperplasia, Cushings syndrome, androgensecreting tumors, thyroid disease, and hyperprolactinemia.
Exclusion criteria
Exclusion criteria: Exclusion criteria for all groups included age > 40 years, or <18 years. PCOS combined with other causes of infertility, known cardiovascular disease, thyroid disease, smoking, diabetes, hypertension. Exclude patients with obvious signs and symptoms of liver and kidney disease, or with a history of drug abuse and alcohol abuse over the past 2 years, or with a history of mental illness, or with infection, trauma, surgery and other emergency situation. Also exclude patients who could not take effective contraceptive measures through the study, or applied with metformin or other euglycemic agent one month before the inclusion or receiving steroid therapy or treatment of malignant tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| insulin resistence;glucolipids metabolism index;sex hormone levels;Insulin resistance and beta-cell function level; | — |
Secondary
| Measure | Time frame |
|---|---|
| anthropometric measurements;menstrual cycle;Fat factor levels;The inflammatory factor level; | — |
Countries
China
Contacts
Public ContactZhang Ying
The third affiliated hospital of Guangzhou Medical University
Outcome results
None listed