The protective effect of nicorandil on heart after off-pump coronary artery bypass grafting patients

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IIR-16008017

Enrollment

Unknown

Registered

2016-02-27

Start date

2016-02-29

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

off-pump coronary artery bypass grafting patients

Interventions

Nic group:Nicorandil

control group:0.9% Nacl

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Adult patients with multiple coronary artery stenosis undergoing OPCAB surgery at the first time.

Exclusion criteria

Exclusion criteria: (1) acute myocardial infarction (AMI) in patients with coronary heart disease (CHD) within one month before operation; (2) preoperative history of diabetes, asthma or bronchial spasm, skeletal muscle disease, immune system disease or other cardiovascular diseases such as II, III degree atrioventricular block, patients with valvular disease; (3) patients with severe liver, renal function and blood system diseases before operation; (4) 70 years of age or older and ejection fraction (EF%) were less than 40%.

Design outcomes

Primary

Measure	Time frame
cTnI;Ck;LDH;LVEDV;EF;	—

Countries

China

Contacts

Public ContactYoujun Luo

18661808970@163.com+86 18661808970

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026