Esophageal varice alone in cirrhosis
Conditions
Interventions
second-look endoscopy group:second-look endoscopy and necessary intervention after 12±2 days of EVL
control group:no second-look endoscopy after EVL and discharge from hospital
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Consecutive patients with decompensated cirrhosis and esophageal varices (diameter between 1.0 cm-2.0 cm),with the age between 18-65 years old and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. With liver cancer (>stage B in Barcelona Clinic Liver Cancer staging classification) or other malignancy; 2. With gastric varices or other ectopic varices; 3. With severe illness in heart, brain, lung or kidney, such as stroke, uremia, acute coronary syndrome, respiratory failure or type I hepatorenal syndrome; 4. No tolerance to endoscopy; 5. Transjugular intrahepatic portosystemic stent shunt or surgery before entry; 6. Total bilirubin>170umol/L or Child-Pugh score>13; 7. melaena or haematemesis, accompanied with requirement for >2 units of packed red blood cells in a 24-hour time period and hemodynamic instability that occurred before second-look endoscopy; 8. Without cirrhosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| re-bleeding rate after 10-30 days of EVL; | — |
Secondary
| Measure | Time frame |
|---|---|
| mortality after 10-30 days of EVL;bleeding related mortality after 10-30 days of EVL; | — |
Countries
China
Contacts
Public ContactAn-Jiang Wang
Outcome results
None listed