A prospective randomized trial to evaluate the effect of lidocaine and epinephrine on prevention of post-ERCP pancreatitis

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IIR-16007942

Enrollment

Unknown

Registered

2016-02-18

Start date

2016-02-15

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-ERCP pancreatitis

Interventions

Lidocaine:Spraying lidocaine on the papilla before cannulation

Epinephrine:Spraying epinephrine on the papilla before cannulation

Lidocaine + Epinephrine:Spraying lidocaine and epinephrine on the papilla before cannulation

Saline:Spraying saline on the papilla before cannulation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Having indications for ERCP. Age 18 years or older. 2. Willing to join the trial and give informed consent. 3. An intact major papilla.

Exclusion criteria

Exclusion criteria: 1. Prior endoscopic sphincterotomy or papilla dilation. 2. Intended for papilla precut. 3. Acute pancreatitis or chronic pancreatitis with an acute exacerbation. 4. Allergic to lidocaine or epinephrine.

Design outcomes

Primary

Measure	Time frame
Incidence of post-ERCP pancreatitis;	—

Secondary

Measure	Time frame
Difficulty of cannulation;	—

Countries

China

Contacts

Public ContactHu Bing

hubingnj@163.com+86 18980601278

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026