A Prospective, Phase II, Randomized control Study of Fertility-sparing Surgery for IB1 Cervical Cancer (squamous/adenocarcinoma) with Tumor 2-4 cm

A Prospective, Phase II, Randomized control Study of Fertility-sparing surgery for IB1 cervical cancer (squamous/adenocarcinoma) with tumor 2-4 cm

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IIR-16007823

Enrollment

Unknown

Registered

2016-01-25

Start date

2016-02-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical cancer

Interventions

Control group:upfront ART treatment

experimental group:NACT

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Confirmed invasive cervical cancer: squamous, adenocarcinoma; 2. Tumor size 2- 4 cm; 3. FIGO stage IB1; 4. Desire to preserve fertility; 5. No clinical evidence of impaired fertility; 6. Chest X-ray with no evidence of metastasis; 7. Preoperative MRI of pelvis and abdomen, or appropriate imaging protocol with no evidence of pelvic lymph node metastases, and confirmation of tumor limited to the cervix; 8. Aged <=40 years.

Exclusion criteria

Exclusion criteria: 1. Tumor metastasis; 2. HIV positive; 3. Cancer history or history of cancer related treatment; 4. Any condition not suitable for chemotherapy of TP regimen; 5. Pregnant or during lactation; 6. Other severe mental or physical illness.

Design outcomes

Primary

Measure	Time frame
Recurrent rate;	—

Secondary

Measure	Time frame
Survival;obstetric outcome;	—

Countries

China

Contacts

Public ContactXIAOHUA WU

docwuxh@hotmail.com+86 64175590-81006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026