esophageal varices in cirrhosis
Conditions
Interventions
experimental group:placing rubber bands as many as possible
controlled group:placing rubber bands up to a maximum of 6 bands
Sponsors
Department of gastroenterology and hepatology, the 1st affiliated hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Consecutive patients with decompensated cirrhosis and esophageal varices (diameter between 1.0 cm-2.0 cm), with the age of 18 to 65 years old and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Use of sclerotherapy 1 year before or at any point after entry; 2. With liver cancer (>stage B in Barcelona Clinic Liver Cancer staging classification) or other malignancy; 3. With gastric varices or other ectopic varices; 4. With severe illness in heart, brain, lung or kidney, such as stroke, uremia, acute coronary syndrome, respiratory failure or type I hepatorenal syndrome; 5. No tolerance to endoscopy; 6. Transjugular intrahepatic portosystemic stent shunt or surgery before entry; 7. Total bilirubin>170umol/L or Child-Pugh score>13; 8. Without cirrhosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time to esophageal variceal obliteration; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time to esophageal variceal recurrence after obliteration;mortality after 6 wks of index ligation;mortality after 1 yr of index ligation;re-bleeding rate after 6 wks of index ligation;re-bleeding rate after 1 yr of index ligation; | — |
Countries
China
Contacts
Public ContactAn-Jiang Wang
Outcome results
None listed