Skip to content

clinical research of Conbercept in the therapy of cataract combined with diabetic macular edema

clinical research of Conbercept in the therapy of cataract combined with diabetic macular edema

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IIR-15007619
Enrollment
Unknown
Registered
2015-12-21
Start date
2015-12-13
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cataract with diabetic macular edema

Interventions

experimental group:Phacoemulsification for cataract + intravitreal Conbercept injection
Control group:Phacoemulsification for cataract

Sponsors

the 4th affiliated hospital of CMU
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: the cataract patients combined with diabetic macular edema, the lens nuclear hardness is in the degree of three, OCT show retinal thickness of macular is greater than 300um, fundus angiography showed that patients with diabetic retinopathy staging is moderate, mild macular edema without ischemic; if both of the eyes are consistent with inclusion criteria, the doctor choose the one eye according to the medical point of view.The control standard of glycosylated hemoglobin was less than 6.5%, the blood glucose was lower than 8mol/L before the meals, and the blood pressure should be less than 160/90mmHg.

Exclusion criteria

Exclusion criteria: 1. the patient contraindicated to FFA; 2. suffer from other macular diseases previously such as age-related macular degeneration, central serous retinopathy; 3. nearly 3 months were treated with glucocorticoid and other anti VEGF drug treatment; 4. combined with anterior segment disease of eyes; 5. the patients with serious heart, brain and liver kidney and hematopoietic system diseases; 6. the patients with malignant tumor; 7. the diopter is higher than 6D.

Design outcomes

Primary

MeasureTime frame
BCVA;protein concentration in aqueous humor;retinal thickness of macular;IOP;

Countries

China

Contacts

Public ContactZhang Jinsong
cmu4h-zjs@126.com+86 18900916888

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026