deep second degree burn with wound infection
Conditions
Interventions
treatment group:NeutroPhase
control group:Prontosan
Sponsors
Changhai hospital, Second Military Medical university
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Aged between 18 to 60 years, Male or female; (2) The clinical diagnosis of deep second degree burn, has been less than 7 days early treatment, the wound was red, swollen, hot, painful or purulent secretion or bacterial positive; (3) The total area of the wound was <10%TBSA (in the palm of the hand), and the wound was between 5cm*5cm~10cm*10cm, wound position for the limbs or trunk; (4) The investigator confirmed that the wounds need to be treated with dressing change; (5) Agreed to participate in the study and signed a written informed consent.
Exclusion criteria
Exclusion criteria: (1) Chemical burn, electric burn, diabetes, and other chronic wounds; (2) Severe malnutrition, albumin 38.5 degree C or WBC>12*10^9/L cell or wound swelling edge>5cm; (4) Subjects were treated with antimicrobial agents for the severe systemic infections; (5) Cancer, radiotherapy or chemotherapy; (6) Combined with severe primary diseases such as cardiovascular, liver, kidney and blood system, or psychotic; (7) Has been known to have a history of allergy to the ingredients of this product and the control, or other chemical structures similar, or allergic constitution (2 and above) of the allergen; (8) Pregnant or lactating women and family planners; (9) The subjects participated in other clinical studies in 1 months before enrolling; (10) The investigator considered that subjects had other conditions that were not suitable for the clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The clinical efficiency of the treatment of the end visit.;The bacterial clearance rate at the end of treatment (clearance rate + assuming removal rate); | — |
Secondary
| Measure | Time frame |
|---|---|
| Bacterial clearance rate of all kinds of pathogenic bacteria in the treatment of fourth days, the end of the treatment.;Target wound healing rate at the end of the treatment; | — |
Countries
China
Contacts
Public ContactZhu Shihui
Outcome results
None listed