HBV cirrhosis
Conditions
Interventions
Experimental Group:Ruangan capsule 100ml bid
Experimental Group:ETV0.5mg/d
Control Group:ETV0.5mg/d
Sponsors
Shenzhen Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. In accordance with the diagnostic criteria of HBV cirrhosis: (1) Serological diagnosis: HBsAg positive and HBV-DNA more than 2000U/L, HBeAg positive or negative; ALT more than 50U/L; (2) TCM diagnosis: According to the diagnosis and treatment protocol for active stage of the HBV cirrhosis (accumulation); (3) Liver pathology diagnosis S3; (4) Imaging score more than 8 point; (5) The hardness of liver fiber scanning more than 12.4 point; 2. In accordance with relevant Ruangan capsule Zheng.
Exclusion criteria
Exclusion criteria: 1. Cirrhosis patients with HBSAG (-); 2. Child score more than 7point; 3. Simultaneous infection with HIV/HCV/HDV; 4. Complicated by metabolic or autoimmune liver disease; 5. With abuse of alcohol or illicit drug history; Involved in other trials of hepatitis drugs within 30 days; 6. Mental illness and other serious organic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultrasonography scoring;Histology of liver biopsy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver function;HBV quantity;Two pairs of semi-quantitative; | — |
Countries
China
Contacts
Public ContactDaqiao Zhou
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed