Efficacy of a new dentifrice containing Chinese herb extracts for gingivitis and Inhibiting dental plaque: a double-blind randomized-controlled trial in adults in China

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IIR-15007562

Enrollment

Unknown

Registered

2015-10-08

Start date

2015-07-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gingivitis

Interventions

The experimental group:Use the pu di lan ke yan ning toothpaste

The control group:Use except pu di lan ke yan ning chinese herb drug ingredients, other ingredients are the same as the pu di lan ke yan ning toothpaste

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Ranging in age from 18 to 70 years old, gender not limited; 2. The body in good health, have a daily habit of brushing your teeth, teeth can be detected more than 20; 3. The subjects have gingivitis; Improved Quigley - Hein plaque index PI >=1.0, and BI index >=1.0; 4. No recent experimental study at the same time to participate in other similar study; 5. Sign the informed consent, can complete the clinical trial as required.

Exclusion criteria

Exclusion criteria: 1. Patients with severe periodontitis, pulpitis or mouth is open cavities, the mucosa lesion; 2. The test of toothpaste ingredients allergies or other oral hygiene products; 3. For nearly three months oral treatment or the use of antibiotics; 4. Have a bad prosthesis; 5. Pregnancy or lactation subjects.

Design outcomes

Primary

Measure	Time frame
Plaque index;Gingival index;Bleeding index;Bleeding on probing proportion;	—

Countries

China

Contacts

Public ContactTao Hu

hutao@scu.edu.cn+86 13980891100

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026