Induced Normal Temperature in severe Traumatic Brain Injury

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IIR-15007514

Enrollment

Unknown

Registered

2015-11-21

Start date

2016-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic Brain Injury

Interventions

Treatment Group:Temperature Control

Control Group:Routine threapy

Eligibility

Sex/Gender

All

Age

16 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 16-65 years; 2. GCS 3-8; 3. The injury mechanism for closed cerebral trauma; 4. Before entering the group - stable hemodynamics, systolic blood pressure > 110mmHg, diastolic blood pressure> 60 mm Hg, the heart rate 35.5 C; 6. Admission less than 8 hours after injury for conservative treatment patients, admission less than 12 hours for patients undergo surgery; 7. No obvious chest trauma.

Exclusion criteria

Exclusion criteria: 1. Pregnant women; 2. Open brain injury, penetrating injury; 3. GCS3 with bilateral mydriasis without light reflex; 4. The other parts of body trauma AIS score > = 4; 5. Continuous hypoxia (oxygen saturation < 94% and greater than 30 minutes).

Design outcomes

Primary

Measure	Time frame
GOSE (6months);GOSE (3months);	—

Secondary

Measure	Time frame
MMSE (6months);Barthel Index (6months);ICP;Coagulation status;safety;	—

Contacts

Public ContactJin HU

15197533@qq.com+86 021 52887732

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026