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Research on prevention of important ocular surface diseases and new diagnosis and treatment technology-----personalized diagnostic methods and integrated control strategy of dry eye

Research on personalized diagnostic methods and related mechanism of dry eye

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IIC-17013940
Enrollment
Unknown
Registered
2017-12-15
Start date
2017-12-18
Completion date
Unknown
Last updated
2017-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry eye

Interventions

normal volunteers:no
dry eye patients:anti-inflammatory drugs

Sponsors

The 2nd Affiliated hospital, Zhejiang University, School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Sign the informed consent of this research voluntarily; 2. healthy volunteers Group 18 years of age or older, no eye discomfort, Schirmer I test = 5mm); 3. Patients with different types of dry eyes.

Exclusion criteria

Exclusion criteria: Meet any one of the following criterias will not be considered eligible for this study: 1. unable or unwilling to complete the questionnaire or do not follow the research procedure; 2. with other eye diseases or general diseases; 3. have the history of using eye or body medicines within 1 week affecting the health of eye surface (except for the use of artificial tears in dry eye patients); 4. wearing contact lens in 1 week.

Design outcomes

Primary

MeasureTime frame
OSDI scale;tear meniscus height;R-scan;Meibo-Scan, observation of Lipid Layer;Observation of corneal epithelial injury by high-definition video;Dry eye comprehensive measurement;Meibomian gland evaluation (MGE) and self-rating scale for patients;slit-lamp examination;confocal microscope examination;

Countries

China

Contacts

Public ContactWen Xu

2nd Affiliated hospital, Zhejiang University, School of Medicine

xuwenhz2002@aliyun.com+86 13858185223

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026