dry eye
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Sign the informed consent of this research voluntarily; 2. healthy volunteers Group 18 years of age or older, no eye discomfort, Schirmer I test = 5mm); 3. Patients with different types of dry eyes.
Exclusion criteria
Exclusion criteria: Meet any one of the following criterias will not be considered eligible for this study: 1. unable or unwilling to complete the questionnaire or do not follow the research procedure; 2. with other eye diseases or general diseases; 3. have the history of using eye or body medicines within 1 week affecting the health of eye surface (except for the use of artificial tears in dry eye patients); 4. wearing contact lens in 1 week.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OSDI scale;tear meniscus height;R-scan;Meibo-Scan, observation of Lipid Layer;Observation of corneal epithelial injury by high-definition video;Dry eye comprehensive measurement;Meibomian gland evaluation (MGE) and self-rating scale for patients;slit-lamp examination;confocal microscope examination; | — |
Countries
China
Contacts
2nd Affiliated hospital, Zhejiang University, School of Medicine