Effect of coenzyme complex on BIS and recovery quality during the general anesthesia emergence period in elderly patients

Study of the effects of coenzyme complex on BIS and recovery quality during the general anesthesia emergence period in elderly patients

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IIC-17010773

Enrollment

Unknown

Registered

2017-03-03

Start date

2017-04-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal cholecystectomy

Interventions

gruop C1:Intravenous infusion of 100U coenzyme complex

gruop C2:Intravenous infusion of 200U coenzyme complex

gruop C:Intravenous infusion of equal capacity of normal saline

Eligibility

Sex/Gender

All

Age

65 Years to 80 Years

Inclusion criteria

Inclusion criteria: Ninety ASA I or II patients aged 65-80 yr undergoing transabdominal cholecystectomy by general anesthesia randomly allocated into three groups(n=30 each)

Exclusion criteria

Exclusion criteria: There were no neurological disorders, no cardiovascular system, respiratory system diseases, no long-term opioids or diazepam, and normal liver and kidney function. Patients with arrhythmia before operation, operation time shorter than 30min, longer than 2h, and intraoperative bleeding more than 400mL were excluded from this study.

Design outcomes

Primary

Measure	Time frame
BIS value;heart rate;Steward awakening score;	—

Countries

China

Contacts

Public ContactWang Wei

Jiangning Hospital of Nanjing

wangwei2024@163.com+86 13851885625

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026