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The clinical effect of different application of Tranexamic acid in peri-operative period of total hip arthroplasty

The clinical effect of different application of Tranexamic acid in peri-operative period of total hip arthroplasty

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IDR-17010966
Enrollment
Unknown
Registered
2017-03-23
Start date
2016-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip osteoarthritis

Interventions

A:topical application
B:intravenous application
C:oral application

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: All patients undergoing primary total hip arthroplasty during study period

Exclusion criteria

Exclusion criteria: allergy to tranexamic acid; preoperative hepatic or renal dysfunction; preoperative use of anticoagular medication seven days prior to surgery; history of fibrinolytic disorder or blood dyscrasia; cerebrovascular accident, myocardial infarction, New York heart association class III or IV heart failure, atrial fibrillation, history of deep vein thrombosis or pulmonary embolus, preoperative INR >1.4, aPTT >1.4 x normal, platelets <140000/mm3.

Design outcomes

Primary

MeasureTime frame
haemoglobin level;Blood loss;Hct;Transfusion;hip function evaluation ;perioperative complications: deep vein thrombosis ;cost;nausea and vomiting;drainage;length of hospital stay;—

Secondary

MeasureTime frame
ESR, CRP, IL-6;sweeling;pain;—

Countries

China

Contacts

Public ContactZhou Zongke

West China Hospital, Sichuan University

zongke@126.com+86 18980601028

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026