Skip to content

Effect of platelet-rich fibrin on the periodontal healing of avulsed tooth reimplantation: a randomized-controlled trial

Effect of platelet-rich fibrin on the periodontal healing of avulsed tooth reimplantation: a randomized-controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-ICR-15007129
Enrollment
Unknown
Registered
2015-09-20
Start date
2014-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tooth avulsion

Interventions

The PRF Group:reimplantation with autologous PRF

Sponsors

School of Stomatology, Fourth Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Over 12 years (tooth with closed apex); 2. Both male andfemale; 3. The position of the avulsed tooth involves the incisor of maxillary andmandibular; 4. The tooth has been out of the alveolar socket over 1 hour; 5. Avulsed tooth was kept in dry or inappropriate so that the periodontal ligament tissues has been necrosis widely; 6. Without root fracture; 7. The patient volunteered for this study andsigned the consent.

Exclusion criteria

Exclusion criteria: The patient who has blood system diseases, especially thrombocytopenia. The patient who suffered from hypertension or hyperlipidemia. The patient who suffered from progressive periodontitis. The patient who suffered from rampant caries without treatment. The patient who smokes long term andlarge amount. The paired jaw tooth of avulsed tooth was absent. The patient who suffered from diabetes without treatment. The patient who has infectious diseases. The patient who has oral mucosal disease or autoimmune disease. The patient who was pregnant or intent to pregnant in recent 2 years. Alcoholics or drug abuser. The patient who needs to take corticosteroids or other hormone medicines. The patient who cant or not willing to cooperate on the study, or couldnt follow-up. The patient who has unreasonable requests.

Design outcomes

Primary

MeasureTime frame
The width of Periodontal membrane accessed by X-ray;Apical shadow accessed by X-ray;Root resorption accessed by X-ray andCBCT;pain of percussion;Tooth mobility;

Secondary

MeasureTime frame
tooth color;gingival index;bleeding on probing;clinical probing depth;fistula;pulp vitality;

Countries

China

Contacts

Public ContactZhang Min
zhangmin@fmmu.edu.cn+86 29-84776488

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026