Acute Ischemic Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. patients aged 18-80 years old; 2. Within 48 hours of onset; 3. curtain ischemic stroke; The clinical neurological deficit: NIHSS score before the cycle by 6 to 22 points; 5. blood pressure <=180/110mmHg; 6. A head CT imaging changes without bleeding; 7. At the first onset or the last onset did not leave again onset of paralysis andother complications, anddoes not affect this NIHSS score, previous onset of this admission mRS score <=1 points; 8. signed informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. serious heart, liver, kidney disease (serum bilirubin, alanine aminotransferase, aspartate aminotransferase 1.5 times higher than normal, blood urea nitrogen, creatinine 1.5 times higher than normal) person; 2. uncontrolled hypertension (blood pressure> 180/110mmHg); 3. hemorrhagic stroke; 4. Patients can not cope with severe disturbance of consciousness in patients with stroke (NIHSS score> 23 points), psychosis, dementia andthe like; 5. atrial fibrillation; 6. Pregnant women, lactation; 7. Plan thrombolytic treatment of patients; 8. used after the onset of neuroprotective agents (such as edaravone, ganglioside, maleic acid cinepazide PL); 9. Because of the presence of comorbid life expectancy of less than six months; Within 10.3 months who are participating in other clinical trials; 11. venipuncture site have infected; 12. Past heparin, calcium allergy; 13. less than 50,000 platelets, coagulation severe abnormalities; 14. Hypoproteinemia; 15. refused to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 90 days mRS score; | — |
Countries
China