caerean section
Conditions
Interventions
A:Injecting 20ml of 0.35% ropivacaine the transversus abdominis plane
B:Injecting 15ml of 0.35% ropivacaine transversus abdominis plane, 5ml internal oblique
C:Injecting 10ml of 0.35% ropivacaine transversus abdominis plane, 10ml internal oblique
D:Injecting 5ml of 0.35% ropivacaine transversus abdominis plane, 15ml internal oblique
Sponsors
The First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: The patients of cerean section, ASA I or II, QTc interval analysis of ECG before operation, QTc<0.47, agreeing that ultrasound guided transversus abdominis plane block is used for multimodal analgesia after cerean section.
Exclusion criteria
Exclusion criteria: Patients are excluded if they are or have: 1. allergic to local anesthetic; 2. abnormal coagulation function; 3. abnormal liver kidney function; 4. history of nerve or muscle abnormalities; 5. history of abdominal surgery or radiotherapy; 6. skin damage infection of abdominal wall; 7. mental illness; 8. unable to understor to express VAS pain scores correctly; 9. taking drugs that affect CYP1A2 metabolism of ROP (eg, fluvoxamine); 10. taking drugs that may prolong QTc interval (eg, haloperidol, amiodarone, sotalol).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS;morphine consumption;the plasma ropivacaine concentrations of 15min, 30min, 2h, 4h after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| presence severity of PONV Sedation at 2h, 4h, 8h, 12h, 24h; | — |
Countries
China
Contacts
Public ContactQun Lin
Outcome results
None listed