Intracranial aneurysm
Conditions
Interventions
Group dexmedetomidine:Dexmedetomidine plus nitroglycerin induced hypotension
Group remifentanil:Remifentanil plus nitroglycerin induced hypotension
Group sevoflurane:Sevoflurane induced hypotension
Sponsors
The first affiliated hospital of Nanchang university
Eligibility
Sex/Gender
All
Age
18 Years to 69 Years
Inclusion criteria
Inclusion criteria: 90 volunteer patients, under the age of 70, hunt and hess grade I to II, American sociaty of Anesthesiologists II to III, at a university hospital undergoing elective intracranial aneurysm clipping.
Exclusion criteria
Exclusion criteria: Preoperative psychosis and inflammation of nervous system, preoperative epilepsy seizure, hemiplegia and aphasia, substantive lesions of vital organs, such as cerebrovascular disease, cardiac dysfunction, renal dysfunction, hepatic dysfunction; cardiovascular disease such as peripheral vascular claudication, organ perfusion deficiency; hypovolemia or severe anemia; severe respiratory system disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hemodynamics;mini-mental state examination scores; | — |
Countries
China
Contacts
Public ContactXiao-bo Hu
Outcome results
None listed