acute ST-segment elevation myocardial infarction
Conditions
Interventions
A:rapid balloon deflation
B:slow balloon deflation
Sponsors
Shanghai Ninth People's Hospital,Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Male and female patients =18 and = 80 years of age; 2. STEMI patients (presenting within 12 h after chest pain onset, with ST-segment elevation=0.1 mV in two contiguous leads on 12-lead electrocardiogram or new left bundle branch block); 3. Target vessel diameter between 2.5mm and 4.0mm; 4. If the target lesion requires stent overlapping, at least 2mm of overlapping section is guaranteed; 5. Visual residual diameter stenosis =70% before stent implantation; 6. Voluntary participation and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Acute occlusive lesion of left main, bypass grafting and in-stent; 2. Cardiogenic shock; 3. High risk of bleeding; 4. Complicated with Other serious diseases (malignant tumor, Organ transplantation or candidate); 5. Allergy to aspirin, heparin, clopidogrel or rapamycin; 6. Severe liver and kidney disfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| corrected TIMI frame count (CTFC) of infarction related artery (IRA); | — |
Secondary
| Measure | Time frame |
|---|---|
| TIMI flow grade (TFG) of IRA;TIMI Myocardial Blush Grades (MBG);TIMI myocardial perfusion grade (TMPG);No-reflow;ST-segment resolution on ECG assessed 2 h after reperfusion;Myocardial enzyme peak;LVEF;final infarct size assessed by MRI at 6 months after reperfusion;MACE in hospital, 30 days, 6 months and 12 months after reperfusion; | — |
Countries
China
Contacts
Public ContactChangqian Wang
Outcome results
None listed