Osteoporosis patients after total hip replacement
Conditions
Interventions
1:zoledronate
Sponsors
Sun yet-sen memorial hospital, Sun yet-sen university
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 40-70; 2. Type A or B of Dorr classification; 3. Prepare to undergo total hip arthroplasty(cementless) because of femoral head fracture or femoral head necrosis; 4. Tolerance operation; 5. Patient and his/her family members agree to accept the operation; 6. Informed consent has been signed.
Exclusion criteria
Exclusion criteria: 1. MNA-SF<11, indicating malnutrition; 2. Dianosised with disease can cause secondary osteoporosis; 3. Dianosised with severe medical disease or tumor; 4. Dianosised with malposition of prosthesis or periprosthesis infection; 5. Has the contraindication of bisphosphonate; 6. Using drugs affecting bone metabolism within 6 months before the operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone density of each Gruen zone;The incidence of aseptic loosening and joint renovation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Whether prosthesis position in the safety zone;With or without bright line around prosthesis,prosthesis handle with or without sinking/acetabular cup with or without presence of tilt or rotate;Harris hip scores;Bone turnover index (beta-CTX and PINP);Adverse drug reactions;Surgical complications;EQ-5D scores; | — |
Countries
China
Contacts
Public ContactYue Ding
Outcome results
None listed