ovarian dysfunction (ovulation failure infertility)
Conditions
Interventions
the treating group:activating renal blood circulation and ovarian stimulation infusion
the control group:clomiphene
Sponsors
China Academy of Traditional Chinese Medicine Xiyuan Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. primary and secondary infertility participants who were under 35 years old not contraceptive 1 year or over 35 years old not contraceptive 6 month; 2. Conform to the diagnostic criterias of dysfunctional uterine bleeding, polycystic ovary syndrom, hyperprolactinemia, Luf follicle unruptured syndrome, luteal phase deficiency and diminished ovarian reserve; 3. Syndrome differentiation of traditional Chinese medicine is kidney deficiency and blood stasis; 4. During the treatment, couples live together and have normal sex life; 5. Each participant freely signs the informed consent.
Exclusion criteria
Exclusion criteria: 1. Infertility caused by congenital brith defect or deformity; 2. Infertility caused by genetic factors; 3. Infertility caused by oviduct, immune factors, endometriosis, uterine muscle adenopathy, uterine fibroids, uterine dysplasia; 4. male reproductive dysfunction; 5. with cardiovascular, liver, kidney and hematopoietic system illness or psychiatric patients; 6. Drug allergy to investigational drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovulation rate;pregnancy rate;TCM symptom score;endometrium;diameter of dominant follicle;Sex hormones; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood routine examination;urinary routine examination;stool routine test;blood coagulation test;electrocardiography;hepatic and renal function test; | — |
Countries
China
Contacts
Public ContactMa Kun
Outcome results
None listed