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Intra-articular injection of Autologous conditioned plasma to treat Knee Osteoarthritis A randomized clinical trial

Intra-articular injection of Autologous conditioned plasma to treat Knee Osteoarthritis A randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-ICR-15006376
Enrollment
Unknown
Registered
2015-05-11
Start date
2015-05-12
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Interventions

control group:Sodium Hyaluronate Injection
treatment group:Autologous conditioned plasma preparation

Sponsors

Gui Zhou Provincial Orthopedic Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: a history of chronic (at least 1 months) pain or swelling of the knee and imaging findings of degenerative changes of the knee joint (Kellgren Lawrence score of I to III on X-ray evaluation or MRI findings of degenerative changes in patients without X-ray evidence of OA.

Exclusion criteria

Exclusion criteria: systemic disorders such as diabetes, rheumatoid arthritis, hematological diseases (coagulopathy), severe cardiovascular diseases, infections, immunodepression, treatment with anticoagulants or antiaggregants, use of nonsteroidal antiinflammatory drugs (NSAIDs) in the five days before blood harvesting, hemoglobin value <11g/dl and platelet count <110,000/mmc.

Design outcomes

Primary

MeasureTime frame
(Western Ontario and McMaster university Osteoarthritis Index, WOMAC;Visual Analogue Scale;—

Countries

China

Contacts

Public ContactQiu Bing
yz8088gk@163.com+86 18908502233

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026