chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Sun Yat-sen memorial hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: All included patients consistent with the diagnosis of "global chronic obstructive pulmonary disease prevention initiative (GOLD)" on severe stable COPD, are ages between 50 to 85 years old, and volunteer to participate in the study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. a recent (less than one month) acute exacerbation COPD; 2. with other respiratory diseases affecting the lung function; 3. serious cardiovascular and cerebrovascular diseases; 4. Lower limb movement disorders; 5. with psychological or systemic disease; 6. ongoing or recently completed (less than 6 weeks) of pulmonary rehabilitation training; 7. other reasons unsuitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| quadriceps endurance;exercise capacity; | — |
Secondary
| Measure | Time frame |
|---|---|
| lung function;St george's respiratory questionaire;maximal inspiratory pressure;inflammatory factor;respiratory neural drive;maximal expiratory pressure;bone density;skeletal muscle related microRNA; | — |
Countries
China
Contacts
Public ContactRui Chen
Outcome results
None listed