Systemic inflammatory response syndrome (SIRS)
Conditions
Interventions
Group D:dexmedetomidine 1ug/kg I.V.
Sponsors
The Third Affiliated Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Volunteered for the patients, and sign the informed consent; 2. 18-65 year old; 3. Complexity kidney stones (casting, multiple stones and huge stones > 2 cm in diameter); 4. ASA I-II; 5. weight 50~80 kg.
Exclusion criteria
Exclusion criteria: 1. The patient refused to participate in this study; 2. The patients with other important organ dysfunction, including serious liver and kidney dysfunction, NYHA >=III level, coagulant function abnormality; 3. with Sick sinus syndrome, bradycardia (HR <55 times/min), more than ?degree atrioventricular block, tachycardia; 4. History of ipsilateral kidney operation; 5. The history of dexmedetomidine allergy; 6. History of neurological and psychiatric diseases, history of long-term use of sedative drugs, or inappropriate patients for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heart rate;breathing rate;temperature;WBC;SCr; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory cytokines;KIM-1; | — |
Countries
China
Contacts
Public ContactShaoli Zhou
Outcome results
None listed