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The brain function influence clinical research of "Kaixin Jieyu fang" for vascular depression patients

The brain function influence clinical research of "Kaixin Jieyu fang" for vascular depression patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-ICR-14005711
Enrollment
Unknown
Registered
2014-11-03
Start date
2014-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vascular depression

Interventions

:medicine intervention

Sponsors

Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. According to recommended diagnostic criteria by David in 1998 and Additional advice by DC Steffens in 2004, Conform to the depression diagnostic criteria and imaging changes in "Chinese spirit of nerve disease classification scheme and diagnostic standard" version 3 (CCMD-3), the clarify diagnosis is Vascular depression patients; 2. TCM differentiation is not only "Qi deficiency" but also "Qi and blood stasis" (primary symptom: be down in spirits,interest blank, lacking in strength. Accompanied symptom: poor appetite, abdominal distension, constipation or loose stools, palpitation and insomnia, amnesia, frequent micturition, chest heave a deep sigh, bronchial foreign body sensation, light and dark tongue, stringy pulse. The primary symptom is necessary, the accompanied sumptom must have more than two above them.); 3. The compliance of patient is good; 4. The age is form 50 to 80; 5. Agree and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Disturbance of consciousness; 2. Obvious ementia symptoms (Simple mental state examination scale MMSE score is less than 17); 3. Serious heart kidney damage and severe hematopoietic system disease; 4. Severe mental disorders; 5. Can't stick to the healer; 6. Take antidepressants or other related drugs in recently one month.

Design outcomes

Primary

MeasureTime frame
Hamilton's Depression Scale;self-rating anxiety scale;mini-mental state examination minimentalstateexam;The doctor of traditional Chinese medicine symptom integral table;diffusion tensor imaging;Blood oxygen level dependent functional magnetic resonance imaging;magnetic resonance spectroscopic imaging;liver function;renal function;blood routine examination;urine routines;electrocardiogram;

Countries

China

Contacts

Public ContactHuang Shijing
gamhsj@126.com+86 13693681458

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026