total knee arthroplasty surgery
Conditions
Interventions
1:CFNB
2:parecoxib sodium
3:Intra articular injection
4:parecoxib sodium and intra articular injection
Sponsors
peking university third hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age between 40-80 years; 2. the weight 40-l00 kg; 3. American Society of Anesthesiology Medical Association (American Society of Anesthesiologists, ASA I-II level; 4. of previously healthy or hypertension grade I, and get effective control, peri operative blood pressure not higher than 140 / 90mmHg. Fifthly, diabetes is less than 5 years, without target organ damage and get effective control, enclosed operative glycemic control in less than 10 mmol / L, and a power and with the ability of informed consent.
Exclusion criteria
Exclusion criteria: 1. have significant psychological problems, a history of mental illness, long-term history of chronic pain and take the town for a long time, painkillers, sedatives, anti depression drugs, anti anxiety drug history, NSAIDs drugs, alcohol and drug abuse history; II have asthma or bronchitis, major cardiovascular disease, liver and kidney function is not complete, gastric ulcer history, coagulation dysfunction; 2. to which any kind of drug allergy history; 3. there suffering from limb neuromuscular defect; fifthly, language and communication difficulties; the patients asked to withdraw.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Countries
China
Contacts
Public ContactXiangyang Guo
Outcome results
None listed