trauma
Conditions
Interventions
TXA group:Intravenous administration of the tranexamic acid (10mg/Kg) before surgery
Control group:Intravenous administration 0.9%NS before surgery
Sponsors
The Military General Hospital of Chengdu, PLA
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: The patients suffer from pelvic fracture who need to undergo internal fixation operation; between 18-70 years old;patient informed consent.
Exclusion criteria
Exclusion criteria: allergy to TXA; hemoglobin <90g/L (female) or <100g/L (male); platelets<150000 mm3; coagulation dysfunction; receiving antiplatelet or anticoagulant therapy; thrombosis embolism history; hypercoagulable state; renal dysfunction; hepatic insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The volume of blood loss during operation;The volume of drainage postoperative;The volume of blood transfusion;Hemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fibrinogen;D- dimer;INR;PT;APTT; | — |
Countries
China
Contacts
Public ContactLiao Dongfa
Outcome results
None listed