Kawasaki disease
Conditions
Interventions
Sponsors
Guangzhou Women and Children's Medical Center
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1. The Kawasaki disease diagnosis is based on diagnostic criteria revised by American Heart Association in 2017: In the presence of fever for at least 5 d (the day of fever onset is taken to be the first day of fever) together with at least 4 of the 5 following principal clinical features. 1) Erythema and cracking of lips, strawberry tongue, and/or erythema of oral and pharyngeal mucosa; 2) Bilateral bulbar conjunctival injection without exudate; 3) Rash: maculopapular, diffuse erythroderma, or erythema multiforme-like; 4) Erythema and edema of the hands and feet in acute phase and/or periungual desquamation in subacute phase; 5) Cervical lymphadenopathy (=1.5 cm diameter), usually unilateral. In the presence of =4 principal clinical features, particularly when redness and swelling of the hands and feet are present, the diagnosis of KD can be made with 4 d of fever, although experienced clinicians who have treated many patients with Kawasaki disease may establish the diagnosis with 3 d of fever in rare cases; 2. Aged between 0 and 18 years.
Exclusion criteria
Exclusion criteria: (1) Incomplete clinical data; (2) No informed consent; (3) Concurrent with other vascular inflammatory diseases; (4) Concurrent with other severe organ system diseases unrelated to Kawasaki disease; (5) Other inappropriate conditions judged by clinicians.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of coronary artery lesions;incidence of intravenous immunoglobulin resistant;morbidity of incomplete Kawasaki disease;incidence of giant coronary artery aneurysm;recurernce rate of Kawasaki disease;white blood cell;C-reactive protein;hemoglobin;platelet;the percentage of neutrophile granulocyte;albumin;erythrocyte sedimentation rate; | — |
Countries
China
Contacts
Public ContactLi Zhang
Guangzhou Women and Children's Medical Center
Outcome results
None listed