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The epidemiological investigation research of the blood coagulation function about Non-transfusion-dependent thalassaemia in Guangxi region

The epidemiological investigation research of the blood coagulation function about Non-transfusion-dependent thalassaemia in Guangxi region

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-EOC-16007840
Enrollment
Unknown
Registered
2016-01-27
Start date
2016-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-transfusion-dependent thalassaemia

Interventions

Case series:Nil

Sponsors

The first affiliated hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The patients must be diagnosed with HbH disease,ß-thalassemia intermedia or HbE/ßthalassemia by hemoglobin electrophoresis, peptide chain analysis and the thalassemia gene detects; 2. There were no regular blood transfusion in the course of the disease; 3. The patients must not accept anticoagulant therapy in a month recent.

Exclusion criteria

Exclusion criteria: The serious primary disease involved with cardiovascular, liver and kidney organs or (and) inherited thrombophilia.

Design outcomes

Primary

MeasureTime frame
Beta-TG;P - select;Tissue factor;Tissue factor pathway inhibitor;F1+2;Thrombin/antithrombin complexes;Protein C;Free protein S;Tissue-type plasminogen activator;Plasminogen activator inhibitor-1;Thrombin activatable fibrinolysis inhibitor;E - select;Von Willebrand Factor;

Secondary

MeasureTime frame
Blood routine;Four coagulation tests;Liver Function;Serum ferritin;

Countries

China

Contacts

Public ContactPeng Cheng
gxchengpeng@163.com+86 13977166448

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026