Non-transfusion-dependent thalassaemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The patients must be diagnosed with HbH disease,ß-thalassemia intermedia or HbE/ßthalassemia by hemoglobin electrophoresis, peptide chain analysis and the thalassemia gene detects; 2. There were no regular blood transfusion in the course of the disease; 3. The patients must not accept anticoagulant therapy in a month recent.
Exclusion criteria
Exclusion criteria: The serious primary disease involved with cardiovascular, liver and kidney organs or (and) inherited thrombophilia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Beta-TG;P - select;Tissue factor;Tissue factor pathway inhibitor;F1+2;Thrombin/antithrombin complexes;Protein C;Free protein S;Tissue-type plasminogen activator;Plasminogen activator inhibitor-1;Thrombin activatable fibrinolysis inhibitor;E - select;Von Willebrand Factor; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine;Four coagulation tests;Liver Function;Serum ferritin; | — |
Countries
China