Type 2 diabetes mellitus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of type 2 diabetes mellitus, WHO,1999; 2. Aged >=50 years; 3. No change in the treatment of blood glucose in the last 3 months; 4. no acute complications of diabetes; 5. no major lifestyle changes including smoking, drinking, exercise, etc.
Exclusion criteria
Exclusion criteria: 1. Type 1 diabetes, gestational diabetes and other special type of diabetes; 2. Had been done a weight loss surgery, or is currently receiving weight loss drug treatment; 3. Weight changed more than 2% over 3 months; 4. Severe acute or chronic hepatitis; 5. serum creatinine>1.5 mg/dL (133 umol/L; male), 1.4mg/dL (124umol/L, female) or eGFR<45ml/min/1.73m2; 6. Combined with other endocrine diseases, including hypothyroidism, Cushing's disease, etc.; 7. Suffering from acute infectious diseases or chronic diseases, such as tuberculosis, malignant tumor, HIV infection, etc.; 8. Suffering from serious life-threatening illness; 9. Severe chronic gastrointestinal diseases; 10. Pregnant or lactating women; 11. Suffering from mental illness; 12. Have participated in clinical trials in 3 months; 13. The researchers don't think suitable; 14. Patients can not cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Routine blood test;alanine aminotransferase;glutamic-oxaloacetic transaminaseAST;glutamyltranspetidaseGGT;Creatinine;Urea nitrogen;Total protein;Albumin;Uric acid;Total cholesterol;Triglyceride;LDL-C;HDL-C;Fasting blood glucose;Postprandial blood glucose;HbA1c;Urine protein;25 hydroxy vitamin D3;Height;Weight;Neck circumference;Waist circumference;Grip strength;Hip circumference;The body composition;Total daily energy intake;Intake of nutrients; | — |
Countries
China