Ketosis-prone type 2 diabetes
Conditions
Interventions
Obese ketosis-prone diabetes (Obese-KPD) group:none
New-onset type 2 diabetes without diabetic ketosis:none
Health Control (HC):none
Lean ketosis prone diabetes (Lean-KPD):none
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. All patients admitted to West China Hospital who meet diagnosis criteria of DKA; 2. Willing to participate in the study protocol; 3. New-onset diabetes within half a year according to the consensus reports of the Experts Committee on Diagnosis and Classification of Diabetes Mellitus and WHO in 1999; 4. Diagnostic Criteria for DKA: Blood glucose >250 mg/dL, arterial or venous pH 3+ or serum beta-hydroxybutyrate >3 mmol).
Exclusion criteria
Exclusion criteria: 1. Those taking medication to alter glucose metabolism; 2. Those with ischemic cardiovascular or cerebrovascular or peripheral vascular diseases; 3. Those having congestive heart failure, anemia, hepatic or renal dysfunction; 4. Pregnancy or bread-feeding; 5. Patients with dementia or persistent altered mental status that would prevent collection of consent form and reliable information; Health Control: The control group was health volunteer. The control subjects had to fulfill the following inclusion criteria: (a) Age from 30 to 55 yrs; (b) No diabetes; (c) First degree relatives without a history of diabetes; (d) No drug treatment nor any disease that could potentially disturb carbohydrate metabolism; (e) BMI within the range of mean± SD of the BMI of the Obese and Lean-groups; (f) No history of hypertension. Altogether, subjects met the inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glucose disposal rate (GDR);Serum antibodies;AIRg; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical characteristics;Laboratory characteristics; | — |
Countries
China
Contacts
Public ContactYerong Yu
Outcome results
None listed