Super-acute Ischemic Stroke
Conditions
Interventions
Gold Standard:
Index test:
Sponsors
Zhengzhou University People's Hospital or Henan Province People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patients with time window between symptom onset and hospital admission from 0 to 12h, the onset time is the finally time of normal state (such as, when patients wake up, the stroke onset to think the time is just or again sleeping); 2) Presence of a hemiparesis at hospital admission (i.e., unilateral paresis of arm and leg), unilateral deep sensation obstacle, aphasia, neglect, homonymous hemianopia, gaze deviation to the contralateral side of the hemiparesis, reduced level of consciousness, etc.; 3) Adults, 18 to 80 years; 4) Having signed the informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients are dignosed with acute ICH or cerebrovascular malformation; 2) Patients had an encephalitis or cephalomeningitis, a pneumonia, a gastroenteritis or a urinary tract infection within nearly three weeks; 3) Patients were excluded if they had a transient ischemic attack, an ischemic stroke, an ICH, a brain trauma, myocardial infarction, myocarditis and pericarditis within 3 months before the index event. 4) Patients had a brain surgery within 3 months; 5) Patients are suffering from some late nervous or mental illnesses such as dementia, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis and schizophrenia, needed 1~2 people to help; 6) Patients had a diagnosis of primary or metastatic brain tumor at any time in their medical history; 7) Patients have a terminal stage disease, such as, left or right heart failure, liver failure, renal failure, and others in a state of cachexia, or dyscrasia; 8) Pregnants or lactating women; 9) Patients have some contraindications of MRI, such as claustrophobia, heart pacemakers, confusion, or metallic implants; 10) Patients are in other clinical researches.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| UCHL1; | — |
Secondary
| Measure | Time frame |
|---|---|
| the size of lesion;NIHSS and GCS score;the classification about ASCO; | — |
Countries
China
Contacts
Public ContactXiong Han
Outcome results
None listed