Dysphagia, cranial nerve palsy, head and neck cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: For Phase 1 Study: Head and neck cancer previously received radiotherapy to the neck. Group 1 : clinical hypoglossal nerve palsy; Group 2: clinical recurrent laryngeal nerve palsy, and Group 3 neither a hypoglossal nor a recurrent laryngeal nerve palsy previously documented and a swallowing performance status scale rating of 1 and no laryngeal penetration or aspiration as observed in FEES. For Phase 2 Study: Previously received radiotherapy to the neck and who currently have symptoms of dysphagia as revealed on fiberoptic endoscopic examination of swallowing (FEES).
Exclusion criteria
Exclusion criteria: History of head and neck surgery; Tumour recurrence; History of neurological disease; Severe trismus; Presence of a pacemaker or cardiac defibrillator; Bleeding tendency or on anticoagulants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HD-sEMG/sEMG values;evoked potential values from the nerve conduction tests; | — |
Secondary
| Measure | Time frame |
|---|---|
| Presence of laryngeal penetration or aspiration;Patient's functional swallowing ability; | — |
Countries
China
Contacts
Department of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong