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Establish andevaluate the effectiveness of the change in NVE as a predictor of successful weaning

Establish andevaluate the effectiveness of the change in NVE as a predictor of successful weaning

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DPC-15007553
Enrollment
Unknown
Registered
2015-09-26
Start date
2016-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mechanically ventilated patients.

Interventions

Gold Standard:
Index test:

Sponsors

West China Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. orally intubated (tube size>7.5 mm); 2. mechanically ventilated for more than 48 hrs; 3. evidence for reversal of the underlying cause for respiratory failure; 4. adequate oxygenation (PaO2/FIO2>200 mmHg; PEEP\8 cmH2O); 5. pH>=7.3; 6. hemodynamic stability (absence of active myocardial ischemia,absence of vasopressor use or\5mcg/kg/min of dopamine or dobutamine, heart rate\140); 7. absence of fever(T8or>10 g/dl in subjects withknown coronary disease; 9. Glasgow coma scale>10; 10. 18 years of age or older.

Exclusion criteria

Exclusion criteria: 1. known upper airway obstruction; 2. copious secretions with cough; 3. do notintubate/resuscitate status; 4. patients were not breathing spontaneously with adequate cough. Coughwas evaluated by placing a white card about 1.5 cm away from the end of the endotracheal tube andasking the patient to cough (3 to 4 times); 5. elder than <18 years old; 6. refused to sign the informed consent; 7. refused or can not be placed Edi catheter placement (such as: esophageal varices or obstruction, have esophagus surgery recently, facial surgery or upper gastrointestinal bleeding).

Design outcomes

Primary

MeasureTime frame
NVE;

Countries

China

Contacts

Public ContactLiang Guopeng
liangguopeng007@163.com+86 18980602239

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026