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Targeted metabolic profiling of tyrosine in urine for colorectal cancer diagnosis

Targeted metabolic profiling of tyrosine in urine for colorectal cancer diagnosis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DOD-16008641
Enrollment
Unknown
Registered
2016-06-14
Start date
2016-06-13
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Interventions

Gold Standard:
Index test:

Sponsors

the First Hospital Affiliated to Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 90 Years

Inclusion criteria

Inclusion criteria: The patients with colorectal polyps or cancer proven by colonoscopy and biopsy were admitted before surgery, chemotherapy and radiotherapy.

Exclusion criteria

Exclusion criteria: The patients who were suffered from specific diseases (i.e., tyrosinaemia, alkaptonuria, phenylketonure, PD, chorea) known to interfere with metabolism of Tyr and documented cases of neuroendocrine neoplasm (i.e., carcinoid tumors, and pheochromocytoma), which are known for affecting the testing results of Tyr, were excluded from the study. According to the results of hospital hematology and imaging examination, the patients with liver and kidney dysfunction, the inflammatory state and other parts in addition to CRC were also excluded from the study .

Design outcomes

Primary

MeasureTime frame
the urinary Tyr test;

Countries

China

Contacts

Public ContactLi Xueliang

the First Hospital Affiliated to Nanjing Medical University

ligakur@aliyun.com+86 13601589718

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026