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A clinical study on early evaluation of the anti-angiogenesis effect in colorectal liver metastase using contrast-enhanced Ultrasonography

A clinical study on early evaluation of the anti-angiogenesis effect in colorectal liver metastase using contrast-enhanced Ultrasonography

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DOD-15006262
Enrollment
Unknown
Registered
2015-04-15
Start date
2015-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Gold Standard:
Index test:

Sponsors

Xijing Hospital of Digestive Diseases, the Fourth Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. aged 18-80; 2. patients with colorectal liver metastase diagnosed by endoscope,have at least a liver metastase lesion and can't accept the treatment of radical resection.There is no special request on the primary site; 3. there is at least a lesion accord with the RECIST standard verified by CT or MRI; 4. patients did not accept the treatment of chemotherapy, anti-angiogenesis therapy and radiotherapy for at least three weeks before the beginning of the experiment; 5. subjects accept the trail and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. hypersensitivity to contrast media; 2. patients can't complete the CEUS; 3. severe cardiopulmonary dysfunction; 4. poorly controlled high blood pressure; 5. pregnant woman; 6. other situations.

Design outcomes

Primary

MeasureTime frame
arrival time;time to peak;base intensity;peak intensity;

Secondary

MeasureTime frame
volume of tumor;

Countries

China

Contacts

Public ContactWangxin
wangx@fmmu.edu.cn+86 13571826689

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026