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Feasibility of Predicting Language Lateralization via Asymmetry of Arcuate Fasciculus through Diffusion Tensor Imaging Based Tractography in Low-grade Gliomas Patients

Feasibility of Predicting Language Lateralization via Asymmetry of Arcuate Fasciculus through Diffusion Tensor Imaging Based Tractography in Low-grade Gliomas Patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DOD-14005710
Enrollment
Unknown
Registered
2014-12-26
Start date
2014-12-28
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glioma

Interventions

Gold Standard:
Index test:

Sponsors

PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. The adult patients aged from 18 to 65 years old; 2. Gender was not limited; 3. Pathological diagnosis was low-grade glioma; 4. The glioma located in or close to Broca's or Wernicke's area; 5. Preoperative language function was unimpaired; 6. Unilateral language dominant hemisphere was defined by Wada test; 7. The patient had sighed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Others did not conform to the inclusion criteria; 2. The patient's arcuate fasciculus was infiltrated and destroyed by the gliomas.

Design outcomes

Primary

MeasureTime frame
Fiber number;Fiber volume;Fractional anisotropy;—

Countries

China

Contacts

Public ContactXiaolei Chen
chxlei@mail.sysu.edu.cn+86 13466703648

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026