Prostate cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 65 years and older adult male, without any irritation and obstruction of lower urinary tract symptoms; 2. Able and willing to provide signed inform consent; 3. no contraindications to MR examination, physical condition can tolerate MRI, biopsy or surgery; 4. not suffering from prostate cancer or other malignancies during five years; 5. without any urinary tract surgery (laser, microwave, radio frequency ablation, stents and other treatment) during a year; 6. the exclusion of other congenital malformations; 7. MRI examination intervals the biopsy or surgical with three weeks.
Exclusion criteria
Exclusion criteria: 1. can not tolerate MRI examination and MRI contraindications; 2. Mild range or sever renal injury, GFR/eGFR less than 60ml/min; 3. Before contrast, serum creatinine more than 144mmol/l; 4. MRI examination and biopsy or surgical interval of more than three weeks; 5. any treatment including radiotherapy, chemotherapy and other treatment for cancer; 6. any evidence of metastasis; 7. combined with other serious diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lesion existence;Sensitivity;Specificity;Accuracy;receiver operating characteristic curve;image quality;ADC value; | — |
Countries
China