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Early detection and intervention of acute exacerbation of chronic obstructive pulmonary disease

Early detection of acute exacerbation of chronic obstructive pulmonary disease: a comprehensive approach based on continous symptom monitoring and biomarkers

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DDT-13003815
Enrollment
Unknown
Registered
2013-11-17
Start date
2014-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructivve pulmonary disease

Interventions

Gold Standard:
Index test:

Sponsors

Zhongshan Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) post-bronchodilator FEV1 (forced expiratory volume in first second of expiration)/ forced vital capacity (FVC) ratio was less than 0.70; (2) inform consent obtained; (3) Stable Group D COPD; (4) 1 or more moderate to severe acute exacerbations in the previous year.

Exclusion criteria

Exclusion criteria: Asthma, chronic kidney disease (CKD; stage 4 and 5), severe liver dysfunction, malignancies, psychiatric diseases

Design outcomes

Primary

MeasureTime frame
moderate to severe acute exacerbations per year;—

Secondary

MeasureTime frame
Direct medical cost of COPD;All-cause mortality;COPD-attributable mortality;post bronchodilator FEV1%predicted;CAT score;mMRC score;—

Countries

China

Contacts

Public ContactJing Zhang

Zhongshan Hospital of Fudan University

zhang.jing@zs-hospital.sh.cn+86 021-64041990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026