Chronic infection with Hepatitis B virus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female aged 18 to 65 years old; 2. HBsAg positive for 6 months; 3. agree to have liver biopsy
Exclusion criteria
Exclusion criteria: 1. Patients with alcoholic liver disease, autoimmune liver disease, heretic liver disease, drug induced liver disease, nonalcoholic liver disease or other chronic liver disease; 2. PLT <80×10^9/L; 3. PTA <=60%; 4. patients with any disease or condition which the investigator or treating physician feels would interfere with the trial or the safety of the subject.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| liver biopsy;serum parameters;radiological parameters;fibroscan test; | — |
Contacts
Department of Infectious Diseases, Peking University First Hospital