chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged 40-85 yrs, both male and female, with or without smoking history, receiving treatment in community hospitals or outpatient department in general hospitals; (2) GOLD Stage I-II COPD: FEV1/FVC=50% predicted, measured 20min after 400ug salbutamol inhalation; (3) With stable COPD: no COPD exacerbation during the latest 4 weeks prior to the recruitment; (4) With capability of communicating via oral conversation or written documents and signing informed consent and with agreement to receive and are capable of participating in study related auxiliary examinations.
Exclusion criteria
Exclusion criteria: (1) Significant diseases other than COPD. A significant disease is defined as a disease or condition which, in the opinion of the investigator, may put the patient at risk because of participation in the study or may influence either the results of the study or the patients ability to participate in the study; (2) Patients with clinical diagnosis of lung cancer, bronchiectasis, pneumoconioses, or other single restricted ventilation; (3) Severe cardiovascular, neural, hepatic, renal and hematologic diseases or malignancies that may interfere with the operation of the study; (4) Patients with history of asthma, allergic rhinitis; (5) With the pulmonary rehabilitation treatment within 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cardiopulmonary exercise test ; | — |
Secondary
| Measure | Time frame |
|---|---|
| pulmonary function test; | — |
Countries
China
Contacts
State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Diseases,First Affiliated Hospital, Guangzhou