breast cancer
Conditions
Interventions
Gold Standard:
Index test:
Sponsors
Breast Disease Center, the First Affiliated Hospital of Third Military University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. The patients primarily diagnosed as having breast cancer have not received any treatment yet; 2. Signed informed consent; 3. 18 to 60 years; 4. Capacity to comply with program; 5. No history of other malignant tumors; 6. Acceptable general condition, ECOG score: 0 to 1; 7. The requirements of blood, liver and kidney function (1) Blood function: 1) absolute neutrophil cell count >=1.5*10^9/L; 2) platelet count >=100*10^9/L; 3) HGB >=100g/L, HCT >=0.30; (2) Liver function: total bilirubin =50 mL/min and urinary protein <2+; (4) Coagulation: within 7 days before enrollment, the international normalized ratio (INR) <=1.5 and partial prothrombin time (PPT or aPTT) <=1.5 ULN.
Exclusion criteria
Exclusion criteria: 1. The female patients in pregnancy or lactation; 2. History of lumpectomy; 3. With clear surgical contraindications; 4. With other diseases, which have not been fully controlled, (the blood sampling may trigger the disease attack; 5. History of blood donation reaction or tardive lipothymia; 6. Associated with coronary heart disease, congestive heart failure, severe aortic stenosis, ventricular arrhythmia, severe hypertension and other cardio-cerebral vascular diseases. The critically ill patients; 7. HGB <100g/L or with bacterial infections; 8. Taking the drugs which inhibit compensatory cardiovascular responses; 9. The other factors unsuitable for the enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival;disease free survival; | — |
Countries
China
Contacts
Public ContactJiang Jun
Outcome results
None listed