Colorectal tumor
Conditions
Interventions
Test 
(ColoClear) 
 
test(Pupu 
Tube)
Sponsors
Colorectal surgery department,Cancer Institute and Hospital,Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 74 Years
Inclusion criteria
Inclusion criteria: ?Enrollees included patients with colorectal cancer, advanced adenoma, and spouses and first-degree relatives of patients with colorectal cancer who were in the colorectal surgery and general surgery centers in each center. First-degree relatives include: parents, children, and siblings (same parents). ?Age 40-74 years old; ?Patients with colorectal cancer and advanced adenoma: all require electronic colonoscopy and pathological diagnosis; ?Spouse of patients with colorectal cancer: over 15 years of marriage age; ? The spouse group and the first-degree relative group must be related to the patient group, but not necessarily 1:1:1.
Exclusion criteria
Exclusion criteria: ? Enrollees cannot or will not accept colonoscopy (with colonoscopy contraindications). ?There are other serious diseases of the digestive tract, such as Crohn's disease and ulcerative colitis. ?Diagnosed patients or their spouses and first-degree relatives were diagnosed with colon cancer-related genetic syndromes, such as hereditary non-polyposis colorectal cancer syndrome (HNPCC), familial mucosal skin pigmentation, gastrointestinal tract Polyposis (Peutz-Jeghers Syndrome), MYH-Associated Polyposis (MYH-Associated Polyposis), Gardner syndrome, Turcot syndrome, Cowden syndrome, Juvenile Polyposis, Cronkhinte-Canada syndrome, Neurofibromatosis, or familial polyp proliferation. ?Severe heart, liver, lung, kidney, blood, and endocrine system diseases. ? Pregnant women, lactating women or women of childbearing age who are about to conceive. ? Patients with other malignant tumors at the same time. ? Subjects who have undergone surgery, radiotherapy, and chemotherapy for bowel cancer and precancerous lesions. ?The research physician believes that there are any circumstances that are not suitable for selection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Positive predictive value;Negative predictive value;Coincidence Rate;Morbidity; | — |
Countries
China
Contacts
Public ContactWang Xishan
Cancer Institute and Hospital,Chinese Academy of Medical Sciences
Outcome results
None listed