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To detect postoperative cognitive dysfunction after genereal anesthesia using functional MRI

To detect postoperative cognitive dysfunction after genereal anesthesia using functional MRI

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DDD-17014002
Enrollment
Unknown
Registered
2017-12-17
Start date
2014-06-01
Completion date
Unknown
Last updated
2018-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive dysfunction

Interventions

Gold Standard:cognitive dysfunction assessment by MMSE
Index test:functional MRI

Sponsors

Shengjing Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to 90 Years

Inclusion criteria

Inclusion criteria: Patients underwent non-neurosurgery with American Society of Anesthesiologists (ASA) classification of I-II and older than 55 years old, as well as preoperative MMSE scores = 24 points

Exclusion criteria

Exclusion criteria: preoperative diseases of the nervous system, history of receiving psychotropic drugs or neurosurgery, preoperative pathological changes of major organs and systems, preoperative diabetes, preoperative hypertension with blood pressure =140/90mmHg, severe hypertension during perioperative period, arrhythmia and other serious complications.

Design outcomes

Primary

MeasureTime frame
cognitive dysfunction;SEN, SPE, ACC, AUC of ROC;—

Countries

China

Contacts

Public ContactMa Ling

Shengjing Hospital of China Medical University

maling27@hotmail.com+86 18940256927

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026