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The use of Transcriptom sequencing, to determine the WOI in RIF patients and the relative genes functions, and its potential in non invasive Endometrium Receptivity Testing

The use of Transcriptom sequencing, to determine the WOI in RIF patients and the relative genes functions, and its potential in non invasive Endometrium Receptivity Testing

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DDD-17013375
Enrollment
Unknown
Registered
2017-11-14
Start date
2017-11-20
Completion date
Unknown
Last updated
2020-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

Gold Standard:The endometrial tissue scanning electron microscopy, endometrial ultrasonography and blood endocrine hormones
receptivity&#32
test RNA&#32
sequencing

Sponsors

Reproductive Medicine Center of Xiangya Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 39 Years

Inclusion criteria

Inclusion criteria: (1) the female aged between 20 to 39 years; (2) body mass index (BMI) ranged from 18 to 25kg/m2; (3) patients with secondary infertility, had intrauterine pregnancy history, their first IVF cycle with tubal factor as the main indication for treatment; or primary infertility patients, their first IVF cycle with male factors as the main indication for treatment; (4) The menstrual cycle is regular (25-35 days) and spontaneous ovulation occurs; (5) normal ovarian response (FSH1.5ng/ml antral follicle count > 5).

Exclusion criteria

Exclusion criteria: (1) endometrial lesions (including intrauterine adhesions, endometrial polyps, endometrial tuberculosis); (2) with hydrosalpinx and without proximal tubal ligation; (3) with myoma or adenomyosis adjacent to uterine cavity; (4) advanced endometriosis (stage III–IV). (5) uterine malformation.

Design outcomes

Primary

MeasureTime frame
intrauterine pregnancy rate;implantation rate;

Secondary

MeasureTime frame
ongoing pregnancy rate;live birth rate;

Countries

China

Contacts

Public ContactYanping Li

Xiangya Hospital of Central South University

lisayanping@sina.com+86 13607317798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 23, 2026