bloodstream infection
Conditions
Interventions
detection 
based 
on 
Sponsors
Beijing Shijitan hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Aged =18 years old (no gender limitation); obtained the agreement of patient; 2. Subjects are definitely diagnosed as sepsis and settle in Beijing Shijitan hospital, Beijing Friendship hospital and Xuanwu hospital, of which syndrome are consistent with International Guidelines for Management of Severe Sepsis and Septic Shock: 2016; 3. Patients consistent with diagnosis criteria of bloodstream infection (promulgated by National Health and Family Planning Commission of the Peoples Republic of China in 2001): patients with invasive spot or migratory lesion; patients with poisoning symptom all over the body without obvious infectious lesion; patients with inexplicable erythra, bleeding spot, enlargement of liver and spleen and increase of neutrophils with nucleus migrating towards the left; patients with systolic pressure lower than 12kPa or descending more than 5.3kPa; patients with pathogens detected by blood culture; 4. Retrospective subgroup analysis is based on Guidelines for the prevention and treatment of intravascular catheter-related infections by critical care medicine branch of Chinese medical association in 2007. Catheter is proved to be infection source if consistent with any situations below: semiquantitative catheter culture is positive once (not less than 15 CFU are detected on each catheter part) or quantitative catheter culture is positive (not less than 1000 CFU are detected on each catheter part) and peripheral venous blood culture is positive with the same detected pathogen as it in catheter part; blood from catheter and peripheral vein is cultured quantitatively and simultaneously and the rate of two colony accounting is not less than 5:1; blood from central vein catheter and peripheral vein is cultured qualitatively and simultaneously and the positive result of central vein catheter blood culture is at least 2 h earlier than peripheral vein blood culture; culture of pus from peripheral blood and catheter outlet is positive and the same pathogens should be detected.;Inclusion criteria: 1. Aged =18 years old (no gender limitation); obtained the agreement of patient; 2. Subjects are definitely diagnosed as sepsis and settle in Beijing Shijitan hospital, Beijing Friendship hospital and Xuanwu hospital, of which syndrome are consistent with International Guidelines for Management of Severe Sepsis and Septic Shock: 2016; 3. Patients consistent with diagnosis criteria of bloodstream infection (promulgated by National Health and Family Planning Commission of the Peoples Republic of China in 2001): patients with invasive spot or migratory lesion; patients with poisoning symptom all over the body without obvious infectious lesion; patients with inexplicable erythra, bleeding spot, enlargement of liver and spleen and increase of neutrophils with nucleus migrating towards the left; patients with systolic pressure lower than 12kPa or descending more than 5.3kPa; patients with pathogens detected by blood culture; 4. Retrospective subgroup analysis is based on Guidelines for the prevention and treatment of intravascular catheter-related infections by critical care medicine branch of Chinese medical association in 2007. Catheter is proved to be infection source if consistent with any situations below: semiquantitative catheter culture is positive once (not less than 15 CFU are detected on each catheter part) or quantitative catheter culture is positive (not less than 1000 CFU are detected on each catheter part) and peripheral venous blood culture is positive with the same detected pathogen as it in catheter part; blood from catheter and peripheral vein is cultured quantitatively and simultaneously and the rate of two colony accounting is not less than 5:1; blood from central vein catheter and peripheral vein is cultured qualitatively and simultaneously and the positive result of central vein catheter blood culture is at least 2 h earlier than peripheral vein blood culture; culture of pus from peripheral blood and catheter outlet is positive and the same pathogens should be detected.;Inclusion criteria: 1. Aged =18 years old (no gender limitation); obtained the agreement of patient; 2. Subjects are definitely diagnosed as sepsis and settle in Beijing Shijitan hospital, Beijing Friendship hospital and Xuanwu hospital, of which syndrome are consistent with International Guidelines for Management of Severe Sepsis and Septic Shock: 2016; 3. Patients consistent with diagnosis criteria of bloodstream infection (promulgated by National Health and Family Planning Commission of the Peoples Republic of China in 2001): patients with invasive spot or migratory lesion; patients with poisoning symptom all over the body without obvious infectious lesion; patients with inexplicable erythra, bleeding spot, enlargement of liver and spleen and increase of neutrophils with nucleus migrating towards the left; patients with systolic pressure lower than 12kPa or descending more than 5.3kPa; patients with pathogens detected by blood culture; 4. Retrospective subgroup analysis is based on Guidelines for the prevention and treatment of intravascular catheter-related infections by critical care medicine branch of Chinese medical association in 2007. Catheter is proved to be infection source if consistent with any situations below: semiquantitative catheter culture is positive once (not less than 15 CFU are detected on each catheter part) or quantitative catheter culture is positive (not less than 1000 CFU are detected on each catheter part) and peripheral venous blood culture is positive with the same detected pathogen as it in catheter part; blood from catheter and peripheral vein is cultured quantitatively and simultaneously and the rate of two colony accounting is not less than 5:1; blood from central vein catheter and peripheral vein is cultured qualitatively and simultaneously and the positive result of central vein catheter blood culture is at least 2 h earlier than peripheral vein blood culture; culture of pus from peripheral blood and catheter outlet is positive and the same pathogens should be detected.;Inclusion criteria: 1. Aged =18 years old (no gender limitation); obtained the agreement of patient; 2. Subjects are definitely diagnosed as sepsis and settle in Beijing Shijitan hospital, Beijing Friendship hospital and Xuanwu hospital, of which syndrome are consistent with International Guidelines for Management of Severe Sepsis and Septic Shock: 2016; 3. Patients consistent with diagnosis criteria of bloodstream infection (promulgated by National Health and Family Planning Commission of the Peoples Republic of China in 2001): patients with invasive spot or migratory lesion; patients with poisoning symptom all over the body without obvious infectious lesion; patients with inexplicable erythra, bleeding spot, enlargement of liver and spleen and increase of neutrophils with nucleus migrating towards the left; patients with systolic pressure lower than 12kPa or descending more than 5.3kPa; patients with pathogens detected by blood culture; 4. Retrospective subgroup analysis is based on Guidelines for the prevention and treatment of intravascular catheter-related infections by critical care medicine branch of Chinese medical association in 2007. Catheter is proved to be infection source if consistent with any situations below: semiquantitative catheter culture is positive once (not less than 15 CFU are detected on each catheter part) or quantitative catheter culture is positive (not less than 1000 CFU are detected on each catheter part) and peripheral venous blood culture is positive with the same detected pathogen as it in catheter part; blood from catheter and peripheral vein is cultured quantitatively and simultaneously and the rate of two colony accounting is not less than 5:1; blood from central vein catheter and peripheral vein is cultured qualitatively and simultaneously and the positive result of central vein catheter blood culture is at least 2 h earlier than peripheral vein blood culture; culture of pus from peripheral blood and catheter outlet is positive and the same pathogens should be detected.;Inclusion criteria: 1. Aged =18 years old (no gender limitation); obtained the agreement of patient; 2. Subjects are definitely diagnosed as sepsis and settle in Beijing Shijitan hospital, Beijing Friendship hospital and Xuanwu hospital, of which syndrome are consistent with International Guidelines for Management of Severe Sepsis and Septic Shock: 2016; 3. Patients consistent with diagnosis criteria of bloodstream infection (promulgated by National Health and Family Planning Commission of the Peoples Republic of China in 2001): patients with invasive spot or migratory lesion; patients with poisoning symptom all over the body without obvious infectious lesion; patients with inexplicable erythra, bleeding spot, enlargement of liver and spleen and increase of neutrophils with nucleus migrating towards the left; patients with systolic pressure lower than 12kPa or descending more than 5.3kPa; patients with pathogens detected by blood culture; 4. Retrospective subgroup analysis is based on Guidelines for the prevention and treatment of intravascular catheter-related infections by critical care medicine branch of Chinese medical association in 2007. Catheter is proved to be infection source if consistent with any situations below: semiquantitative catheter culture is positive once (not less than 15 CFU are detected on each catheter part) or quantitative catheter culture is positive (not less than 1000 CFU are detected on each catheter part) and peripheral venous blood culture is positive with the same detected pathogen as it in catheter part; blood from catheter and peripheral vein is cultured quantitatively and simultaneously and the rate of two colony accounting is not less than 5:1; blood from central vein catheter and peripheral vein is cultured qualitatively and simultaneously and the positive result of central vein catheter blood culture is at least 2 h earlier than peripheral vein blood culture; culture of pus from peripheral blood and catheter outlet is positive and the same pathogens should be detected.
Exclusion criteria
Exclusion criteria: 1. Patients who settle in hospital for less than 24 h; 2. Patients with acute or chronic infectious diseases; 3. Patients who need urgent rescue or are approaching death; 4. Patients with psychogenia; 5. Special groups (the pregnant, et al); 6. Patients who use antibacterials 2 weeks before blood collection.;Exclusion criteria: 1. Patients who settle in hospital for less than 24 h; 2. Patients with acute or chronic infectious diseases; 3. Patients who need urgent rescue or are approaching death; 4. Patients with psychogenia; 5. Special groups (the pregnant, et al); 6. Patients who use antibacterials 2 weeks before blood collection.;Exclusion criteria: 1. Patients who settle in hospital for less than 24 h; 2. Patients with acute or chronic infectious diseases; 3. Patients who need urgent rescue or are approaching death; 4. Patients with psychogenia; 5. Special groups (the pregnant, et al); 6. Patients who use antibacterials 2 weeks before blood collection.;Exclusion criteria: 1. Patients who settle in hospital for less than 24 h; 2. Patients with acute or chronic infectious diseases; 3. Patients who need urgent rescue or are approaching death; 4. Patients with psychogenia; 5. Special groups (the pregnant, et al); 6. Patients who use antibacterials 2 weeks before blood collection.;Exclusion criteria: 1. Patients who settle in hospital for less than 24 h; 2. Patients with acute or chronic infectious diseases; 3. Patients who need urgent rescue or are approaching death; 4. Patients with psychogenia; 5. Special groups (the pregnant, et al); 6. Patients who use antibacterials 2 weeks before blood collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| detection report time of pathogen; | — |
Countries
China
Contacts
Public ContactDan Yan;Dan Yan;Dan Yan;Dan Yan;Dan Yan ;;;;
Beijing Shijitan hospital, Capital Medical University;Beijing Shijitan hospital, Capital Medical University;Beijing Shijitan hospital, Capital Medical University;Beijing Shijitan hospital, Capital Medical University;Beijing Shijitan hospital, Capital Medical University
Outcome results
None listed